Basel is the capital of the canton of Basel-Stadt. After the Rauricans, Helvetians and Romans, the Alamanni settled in Basel. At times, Basel was part of the Holy Roman Empire. In 1501 Basel joined the Swiss Confederation. Until 1529 Basel was a bishopric. The university was founded in 1460. Basel is an important location for the pharmaceutical industry. The Botanical Garden of the University of Basel is the oldest botanical garden in Switzerland. The Victoria-House was built in 1898 for the giant water lily Victoria regia.