View of the ruins of the Convento de las Concepcionistas within Panamá Viejo, a UNESCO world heritage site located in Panamá City, Panamá.  More info below:

Panamá Viejo, established initially as Castilla del Oro, was founded after the Spanish discovery of the South Sea in 1513.  On August 15, 1519, Pedro Arias Dávila founded a settlement making it the first European settlement on the Pacific coast. Afterwards, Spanish ambitions in the Americas made Panamá Viejo a vital hub for exploration, trade, and colonial administration. Throughout the 16th and 17th centuries, Panama became a crucial transit point for wealth extracted from South America, particularly gold and silver bound for Spain.

The strategic location of Panamá Viejo, combined with its status as a Royal Court of Justice seat, cemented its importance in the Spanish Empire. Its economic role is reflected in the imposing stone structures that once adorned the city, including public and religious buildings that were architectural feats of the time.

However, the city faced numerous challenges during its 152 years of existence. It was repeatedly affected by fires, earthquakes, and slave rebellions, but the most devastating event occurred in 1671 when English pirate Henry Morgan sacked and burned the city. Panamá Viejo was abandoned following this attack, and the town was relocated to a more defensible location.

From: https://lacgeo.com/panama-viejo-casco-antigua